Molecular Formula | C17H12O7 |
Molar Mass | 328.27 |
Density | 1.3358 (rough estimate) |
Melting Point | 299℃ |
Boling Point | 386.03°C (rough estimate) |
Specific Rotation(α) | D -280° (c = 0.1 in DMF) |
Flash Point | 11 °C |
Solubility | Soluble in chloroform. |
Appearance | White to yellow powder. |
BRN | 1630643 |
pKa | 10.76±0.20(Predicted) |
Storage Condition | 2-8°C |
Sensitive | Sensitive to light |
Refractive Index | 1.4790 (estimate) |
MDL | MFCD00871812 |
Physical and Chemical Properties | Bioactive Aflatoxin M1 is the main metabolite of Aflatoxin B1. Aflatoxin M1 is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus. The order of toxicity was Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2. |
Use | Product description Aflatoxin is a toxic metabolite of Aspergillus flavus and Aspergillus parasiticus. It is a kind of compound with basic structure containing difuran ring and coumarin (oxonaphtho ketones). Twelve kinds have been isolated and identified. Aflatoxin is easily soluble in chloroform and methanol but insoluble in n-hexane, petroleum ether and ether. Fluorescence is generated under long-wave ultraviolet light, which is named B1,B2,G1,G2,M1,M2,P1,R1,GM and toxic alcohol according to different fluorescence colors, RF values and structures. Among them, B1 has the highest yield, the greatest toxicity and the strongest carcinogenicity. Aflatoxin is heat-resistant and can only be cracked at 280 ℃, so there is little damage at general cooking temperature. It is very stable in neutral and weak acidic solution, slightly decomposed in acidic solution with pH 1~3, and rapidly decomposed and destroyed in solution with pH 9~10. In 1961, it was discovered that peanut cakes contaminated by Aspergillus flavus can induce liver cancer in rats. In 1962, aflatoxin was identified and proved to be a strong carcinogen. Aflatoxin with double bonds at the end of difuran ring in the structure is easy to form epoxidation metabolites and enhance its toxicity, carcinogenicity and mutagenicity. Aflatoxin mainly pollutes grain and oil and its products, such as peanuts, peanut oil, corn, rice and cottonseed. Aflatoxin B1 is used as the pollution index in domestic food testing, which can be detected by thin layer chromatography and high pressure liquid phase method. |
Risk Codes | R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. R40 - Limited evidence of a carcinogenic effect R39/23/24/25 - R23/25 - Toxic by inhalation and if swallowed. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable R36 - Irritating to the eyes R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R45 - May cause cancer |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24 - Avoid contact with skin. S16 - Keep away from sources of ignition. S7 - Keep container tightly closed. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S28 - After contact with skin, wash immediately with plenty of soap-suds. |
UN IDs | UN 3462 6.1/PG 1 |
WGK Germany | 3 |
RTECS | GY1880000 |
FLUKA BRAND F CODES | 10-23 |
HS Code | 29322090 |
Hazard Class | 6.1(a) |
Packing Group | I |
Toxicity | LD50 orally in day old Pekin ducklings: 16.6 mg/duckling (Holzapfel, Steyn) |
category | toxic substances |
Toxicity classification | highly toxic |
acute toxicity | oral-rat LDL0:1.50 mg/kg |
flammability hazard characteristics | Combustible; burning releases stimulating smoke |
storage and transportation characteristics | The warehouse is ventilated and dry at low temperature; stored separately from food ingredients |
fire extinguishing agent | Dry powder, foam, sand, carbon dioxide, mist water |